淫羊藿

淫羊藿/仙灵脾

三枝九叶草(学名:Epimedium sagittatum)是小檗科淫羊藿属的植物。分布在日本以及中国大陆的江西、陕西、湖南、四川、浙江、广西、安徽、湖北、福建、甘肃、广东等地,生长于海拔200米至1,750米的地区,一般生于山坡草丛中、水沟边、林下、灌丛中及岩边石缝中,目前尚未由人工引种栽培。

据记载,南北朝时的著名医学家陶弘景是个业精于勤、对中医药具有执着追求的人。一日采药途中,他忽听一位老羊倌对旁人说:有种生长在树林灌木丛中的怪草,叶青,状似杏叶,一根数茎,高达一、二尺。公羊啃吃以后,阴茎极易勃起,与母羊交配次数也明显增多,而且阳具长时间坚挺不痿。谁知说者无心,听者有意。陶弘景暗自思忖:这很可能就是一味还没被发掘的补肾良药。于是,他不耻下问,虚心向羊倌实地请教,又经过反复验证,果然证实这野草的强阳作用不同凡响。后将此药载入药典,并由此得名“淫羊藿”。

临床应用

  1. 治疗小儿麻痹症
    取淫羊藿、桑寄生等量,制成每2毫升含生药各1克的注射液。急性期以肌肉注射为主,配合穴位注射。肌肉注射每次2毫升,每日2次,连续20天。恢复期及后遗症期以穴位注射为主,配合肌肉注射。穴位注射按常规取穴,每穴注射1~2毫升,隔日1次,连续20天,休息半月再继续治疗。治疗各期小儿麻痹症共246例,其中急性期患者34例,痊愈8例,基本痊愈16例,显著有效7例,有效2例,无效1例;恢复期患者43例,痊愈21例,有效15例,进步5例,无效2例;后遗症期患者共169例,痊愈及基本痊愈9例,显著有效及有效129例,无效31例。据观察,该品对急性期及刚进入恢复期的病例疗效显著,恢复较快。对后遗症期也有一定效果,用药后患肢普遍有发热、有劲等感觉,有效病例可见肌肉逐渐恢复,患肢增粗;其中以一下肢麻痹者疗效较好,上肢麻痹及年龄较大者疗效较差。用药后除有口干现象外,未见其它副作用。
  2. 治疗神经衰弱
    一用3%淫羊藿煎液游子透入法,每日1次,10~20次为一疗程。少数患者另服镇静剂。观察104例,痊愈22例,显著进步21例,进步46例,无效15例。疗程长者疗效较好;治疗后症状开始好转愈早,疗效愈好,而治疗15次病情仍无好转者,即使继续治疗,疗效亦不显著,且不巩固。少数病例治疗初期可出现轻度反应或症状暂时加重,但继续治疗即迅速消失。二用20%淫羊藿酊每次5毫升,每日3次饭前服,连续2~3月。治疗50例,约有80%患者治后症状消除或减轻。服药期间未见不良反应,但不适用于兴奋过程占优势或性欲亢进,及高血压患者。
  3. 治疗慢性气管炎
    以单味淫羊藿丸观察1000余例,一疗程的有效率为74.6%,近期控制和显效率为22.1%。如配合矮地茶等组成复方治疗,疗效有所提高。实践证明,单纯型的疗效优于喘息型,年龄大者疗效较差,但病程长短与疗效无明显关系;祛痰、镇咳作用较好,平喘较差;经治两个疗程者比一个疗程的近期控制和显效率有显著提高。观察中曾对经治一疗程的110例进行随访,结果半年后的有效率为59.1%,较原来疗效下降26.1%。制剂及用法:取淫羊藿茎、叶(干品),以其总量的80%煎取浓汁,20%研粉,两者混合为丸。每日量相当于生药1两,两次分服。治疗中曾以相当于生药5钱和1.5两的剂量(一日量),分别对部分病例进行观察,结果疗效与日服1两者均基本相似。服药后部分病例有轻微反应,以口干、恶心为多见,其次为腹胀、头晕,一般可自行消失。
  4. 对内分泌的作用
    淫羊藿能促进性功能是由于精液分泌亢进,精囊充满后,刺激感觉神经,间接兴奋性欲而引起。
  5. 对免疫系统功能的影响
    肾虚病人T细胞数量、淋转率、抗体、抗原以及网状内皮系统吞噬功能低下,而经过淫羊藿等补肾药治疗均可提高。
    研究表明,淫羊藿多糖有增强机体免疫功能的作用,淫羊藿多糖通过对脾脏抗体生成细胞的影响,既增加脾脏抗体生成细胞数,又促进每个浆细胞产生抗体。
    抗衰老作用,淫羊藿可以从不同方面影响衰老机制。如影响细胞传代,延长生长期,调节免疫和分泌系统,改善机体代谢和各器官功能。根据中医“正气虚”可导致衰老的理论。采用“扶正固本”的治则,保持正常的肾上腺皮质功能和免疫功能,可推迟老化进程和防止老年病的发生。而淫羊藿总黄酮具有增强T细胞免疫和B细胞免疫以及肾上腺皮质的功能,说明淫羊藿的延缓衰老作用与免疫系统的功能有关。
  6. 对心血管系统的作用
    用淫羊藿煎剂和提取物对垂体后叶素引起的大鼠心肌缺血有一定保护作用。降压作用,淫羊藿煎剂及水煎乙醇浸出液给兔(2.5ml/kg)、猫(2ml/kg)及大鼠(4ml/kg)静注,均呈降压作用。其中以对兔作用最明显。
  7. 对血液系统的作用
    淫羊藿煎剂、多糖和总黄酮对血小板聚集性的作用比较,健康人口服淫羊藿煎剂后,红血球压积明显减少,红细胞电泳时间缩短,血沉加快,从而使全血比粘度明显降低。
  8. 对代谢的影响
    淫羊藿有促进DNA合成的作用。
  9. 抗骨质疏松作用
    实验证明,淫羊藿具有促进骨髓细胞DNA的合成作用,说明淫羊藿具有良好的防治骨质疏松的作用。
  10. 对微生物的影响
    淫羊藿煎剂试管内对脊髓灰质炎病毒有显著的抑制作用,在药物与病毒接触1小时内,即表现灭活作用,对其他肠道病毒亦能抑制;对白色葡萄球菌、金黄色葡萄球菌有显著抑菌作用,对奈氏卡他球菌、肺炎双球菌、流感嗜血杆菌有轻度抑制作用。1%浓度对人型结核杆菌有抑菌效力。
  11. 镇咳、祛痰与平喘作用
    淫羊藿的各种制剂中,以茎叶鲜品提取物C及淫羊藿复方Ⅱ号(淫羊藿:桉叶:洋金花=8:2:1)有一定的祛痰作用(小鼠酚红法),乙酸乙酯提取物初步认为有镇咳作用(SO2引起小鼠咳嗽方法),对豚鼠支气管哮喘的平喘作用不够理想。

但需要提醒的是,有口干、手足心发热、潮热、盗汗等症状,属中医学阴虚相火易动者,则不宜服用淫羊藿。

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